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Certain zoonotic bacterial diseases

DOID EFO MESH SNOMED PheWeb

AB1_ZOONOTIC_BACTERIAL

Yersinia pestis infectious disease: Plague is a severe bacterial infection caused by the gram-negative bacterium Yersinia pestis.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 A20-A28
Hospital discharge: ICD-9 02[0-7]|B783A
Hospital discharge: ICD-8 02[0-7]
Cause of death: ICD-10 A20-A28
Cause of death: ICD-9 02[0-7]|B783A
Cause of death: ICD-8 02[0-7]

401

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

401

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Check minimum number of events None

401

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Include endpoints

401

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AB1_ZOONOTIC_BACTERIAL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 401 200 201
Unadjusted prevalence (%) 0.11 0.10 0.13
Mean age at first event (years) 48.69 45.27 52.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.70 [0.67, 4.33] 2.7e-1 50
15 years 0.01 0.78 [0.31, 1.97] 6.0e-1 12
5 years 0.01 3.78 [1.82, 7.84] 3.6e-4 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_ZOONOTIC_BACTERIAL – Certain zoonotic bacterial diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Certain zoonotic bacterial diseases
after Certain zoonotic bacterial diseases

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Drugs most likely to be purchased after Certain zoonotic bacterial diseases

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