Degeneration of nervous system due to alcohol

ALCONEURODEGEN

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G31.2
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G31.2
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

549

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

549

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Check minimum number of events None

549

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Include endpoints None

549

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ALCONEURODEGEN

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G31
Name in latin Degeneratio systematis nervosi ex alcohol (aethylico)

Summary Statistics

Key figures

All Female Male
Number of individuals 549 85 464
Unadjusted prevalence (%) 0.15 0.04 0.29
Mean age at first event (years) 59.48 55.82 60.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.23 15.89 [9.58, 26.34] 7.9e-27 206
15 years 0.06 8.27 [5.92, 11.54] 2.4e-35 84
5 years 0.01 11.63 [8.65, 15.65] 2.6e-59 65
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ALCONEURODEGEN – Degeneration of nervous system due to alcohol
GWS hits:

Survival analyses between endpoints

Plot

before Degeneration of nervous system due to alcohol
after Degeneration of nervous system due to alcohol

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Drugs most likely to be purchased after Degeneration of nervous system due to alcohol