Acohol-induced acute pancreatitis

ALCOPANCACU

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K85.2
Hospital discharge: ICD-9 5770D|5770E
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K85.2
Cause of death: ICD-9 5770D|5770E
Cause of death: ICD-8 $!$

842

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

842

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Check minimum number of events None

842

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Include endpoints None

842

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ALCOPANCACU

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K85

Summary Statistics

Key figures

All Female Male
Number of individuals 842 159 683
Unadjusted prevalence (%) 0.24 0.08 0.43
Mean age at first event (years) 48.12 46.83 48.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.03 [2.36, 6.91] 3.7e-7 158
15 years 0.02 2.63 [1.70, 4.07] 1.4e-5 61
5 years 0.00 3.82 [2.32, 6.28] 1.3e-7 24
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ALCOPANCACU – Acohol-induced acute pancreatitis
GWS hits: 3

Survival analyses between endpoints

Plot

before Acohol-induced acute pancreatitis
after Acohol-induced acute pancreatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acohol-induced acute pancreatitis