Autoimmune diseases excluding thyroid diseases, strict definition

AUTOIMMUNE_NONTHYROID_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not HYPOTHY_LEVOTHY
and not GRAVES_COND
and not E4_HYTHY_AI_STRICT
and not AUTOIMMUNE_HYPERTHYROIDISM

307865

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

47071

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AUTOIMMUNE_NONTHYROID_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 47071 24704 22367
Unadjusted prevalence (%) 13.23 12.45 14.21
Mean age at first event (years) 45.41 43.40 47.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.31 [2.05, 2.59] 2.1e-45 5693
15 years 0.01 1.59 [1.45, 1.75] 9.9e-22 2498
5 years 0.00 2.76 [2.52, 3.02] <1e-100 1410
1 year 0.00 5.95 [5.26, 6.74] <1e-100 607

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AUTOIMMUNE_NONTHYROID_STRICT – Autoimmune diseases excluding thyroid diseases, strict definition
GWS hits: 46

Survival analyses between endpoints

Plot

before Autoimmune diseases excluding thyroid diseases, strict definition
after Autoimmune diseases excluding thyroid diseases, strict definition

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Drugs most likely to be purchased after Autoimmune diseases excluding thyroid diseases, strict definition