Benign neoplasm of bone and articular cartilage

CD2_BENIGN_BONE_CARTILAGE

chondrosarcoma: A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D16
Cause of death: ICD-10 D16

1413

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1413

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Check minimum number of events None

1413

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CD2_BENIGN_BONE_CARTILAGE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D10-D36
Name in latin Neoplasma benignum ossis sive cartilaginis articularis

Similar endpoints

List of similar endpoints to Benign neoplasm of bone and articular cartilage based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 2111 1250 861
Unadjusted prevalence (%) 0.59 0.63 0.55
Mean age at first event (years) 39.46 39.06 40.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.98 [0.49, 1.98] 9.6e-1 140
15 years 0.01 0.72 [0.39, 1.35] 3.1e-1 54
5 years 0.00 1.53 [0.85, 2.76] 1.6e-1 26
1 year 0.00 3.93 [1.92, 8.02] 1.7e-4 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_BONE_CARTILAGE – Benign neoplasm of bone and articular cartilage
GWS hits:

Survival analyses between endpoints

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before Benign neoplasm of bone and articular cartilage
after Benign neoplasm of bone and articular cartilage

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Drugs most likely to be purchased after Benign neoplasm of bone and articular cartilage