Benign neoplasm: Choroid

CD2_BENIGN_CHOROID

choroid cancer: Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D31.3&
Hospital discharge: ICD-9 2246
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 D31.3&
Cause of death: ICD-9 2246
Cause of death: ICD-8 $!$

1165

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1165

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Check minimum number of events None

1165

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Include endpoints None

1165

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CD2_BENIGN_CHOROID

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D31
Name in latin Neoplasma benignum chorioideae

Summary Statistics

Key figures

All Female Male
Number of individuals 1165 699 466
Unadjusted prevalence (%) 0.33 0.35 0.30
Mean age at first event (years) 62.66 60.65 65.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.87 [1.57, 5.22] 5.7e-4 78
15 years 0.01 1.64 [0.87, 3.08] 1.3e-1 40
5 years 0.00 2.38 [1.26, 4.46] 7.1e-3 25
1 year 0.00 4.96 [2.35, 10.47] 2.6e-5 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_CHOROID – Benign neoplasm: Choroid
GWS hits: 1

Survival analyses between endpoints

Plot

before Benign neoplasm: Choroid
after Benign neoplasm: Choroid

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Drugs most likely to be purchased after Benign neoplasm: Choroid