Benign neoplasm of middle ear and respiratory system

CD2_BENIGN_EAR_RESP

cutaneous melanoma: A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D14
Cause of death: ICD-10 D14

1741

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1741

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Check minimum number of events None

1741

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CD2_BENIGN_EAR_RESP

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D10-D36
Name in latin Neoplasma benignum auris mediae sive systematis respiratorii

Similar endpoints

List of similar endpoints to Benign neoplasm of middle ear and respiratory system based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 2069 857 1212
Unadjusted prevalence (%) 0.58 0.43 0.77
Mean age at first event (years) 54.45 50.90 56.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.98 [1.42, 2.75] 5.3e-5 331
15 years 0.01 1.14 [0.83, 1.55] 4.2e-1 144
5 years 0.00 2.28 [1.71, 3.04] 2.2e-8 92
1 year 0.00 4.45 [2.98, 6.63] 2.4e-13 34

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_EAR_RESP – Benign neoplasm of middle ear and respiratory system
GWS hits:

Survival analyses between endpoints

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before Benign neoplasm of middle ear and respiratory system
after Benign neoplasm of middle ear and respiratory system

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Drugs most likely to be purchased after Benign neoplasm of middle ear and respiratory system