Leiomyoma of uterus

CD2_BENIGN_LEIOMYOMA_UTERI

uterine fibroid: A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 D25
Hospital discharge: ICD-9 218
Hospital discharge: ICD-8 21899
Cause of death: ICD-10 D25
Cause of death: ICD-9 218
Cause of death: ICD-8 21899

29388

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

29349

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Check minimum number of events None

29349

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Include endpoints None

29349

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CD2_BENIGN_LEIOMYOMA_UTERI

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D10-D36
Name in latin Leiomyoma uteri

Summary Statistics

Key figures

All Female Male
Number of individuals 29349 29349 -
Unadjusted prevalence (%) 8.25 14.79 -
Mean age at first event (years) 46.99 46.99 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.44 [0.38, 0.50] 2.6e-30 1486
15 years 0.00 0.31 [0.27, 0.36] 3.5e-55 520
5 years 0.00 0.32 [0.26, 0.40] 3.9e-24 110
1 year 0.00 0.47 [0.32, 0.70] 2.3e-4 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_LEIOMYOMA_UTERI – Leiomyoma of uterus
GWS hits: 86

Survival analyses between endpoints

Plot

before Leiomyoma of uterus
after Leiomyoma of uterus

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Drugs most likely to be purchased after Leiomyoma of uterus