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Chronic myeloproliferative disease

DOID EFO SNOMED PheWeb

CHRONMYELOPRO

chronic myeloproliferative disorder: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D47.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 D47.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

298

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

298

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Check minimum number of events None

298

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Include endpoints None

298

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CHRONMYELOPRO

Extra metadata

First used in FinnGen datafreeze DF2, additional

Summary Statistics

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Key figures

All Female Male
Number of individuals 298 134 164
Unadjusted prevalence (%) 0.08 0.07 0.10
Mean age at first event (years) 62.95 61.17 64.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHRONMYELOPRO – Chronic myeloproliferative disease
GWS hits: 1

Survival analyses between endpoints

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Plot

before Chronic myeloproliferative disease
after Chronic myeloproliferative disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic myeloproliferative disease

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