Vitamin B12 deficiency anaemia

D3_ANAEMIA_B12_DEF

vitamin B12 deficiency: A disease characterized by low serum levels of vitamin B12, either inherited or acquired.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D51
Hospital discharge: ICD-9 281[0-1]
Hospital discharge: ICD-8 281[0-1]
Cause of death: ICD-10 D51
Cause of death: ICD-9 281[0-1]
Cause of death: ICD-8 281[0-1]
KELA reimbursements: KELA codes 107

3130

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3130

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Check minimum number of events None

3130

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Include endpoints None

3130

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D3_ANAEMIA_B12_DEF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D50-D53
Name in latin Anaemia ex deficientia vitamini B12

Summary Statistics

Key figures

All Female Male
Number of individuals 3130 1566 1564
Unadjusted prevalence (%) 0.88 0.79 0.99
Mean age at first event (years) 60.66 56.90 64.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.33 [1.70, 3.19] 1.2e-7 882
15 years 0.01 1.25 [0.97, 1.62] 8.7e-2 341
5 years 0.00 2.93 [2.42, 3.55] 3.6e-28 282
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_ANAEMIA_B12_DEF – Vitamin B12 deficiency anaemia
GWS hits: 10

Survival analyses between endpoints

Plot

before Vitamin B12 deficiency anaemia
after Vitamin B12 deficiency anaemia

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Drugs most likely to be purchased after Vitamin B12 deficiency anaemia