Hyposplenism

D3_HYPOSPLENISM

splenic disease: A disease involving the spleen.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D73.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 D73.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

29

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

29

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Check minimum number of events None

29

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Include endpoints None

29

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D3_HYPOSPLENISM

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D73
Name in latin Hyposplenismus

Summary Statistics

Key figures

All Female Male
Number of individuals 29 18 11
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 57.99 54.07 64.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_HYPOSPLENISM – Hyposplenism
GWS hits:

Survival analyses between endpoints

Plot

before Hyposplenism
after Hyposplenism

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