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Sickle-cell disorders

DOID EFO MESH PheWeb

D3_SICKLECELLDIS

obsolete_sickle cell disease: ['A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia.']

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D57
Hospital discharge: ICD-9 282[5-6]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 D57
Cause of death: ICD-9 282[5-6]
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

63

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D3_SICKLECELLDIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D55-D59
Name in latin Morbi meniscocytici

Summary Statistics

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Key figures

All Female Male
Number of individuals 63 33 30
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 52.43 54.66 49.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_SICKLECELLDIS – Sickle-cell disorders
GWS hits:

Survival analyses between endpoints

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Plot

before Sickle-cell disorders
after Sickle-cell disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Sickle-cell disorders

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