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Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

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E4_HYTHY_AI_EXCL

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E8901|E8909|E23|D352|E0382|E05[1-9]|E0[0-2]
Hospital discharge: ICD-9 253
Hospital discharge: ICD-8 253
Cause of death: ICD-10 E8901|E8909|E23|D352|E0382|E05[1-9]|E0[0-2]
Cause of death: ICD-9 253
Cause of death: ICD-8 253
Operations: NOMESCO codes ^BAA60

9994

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

9975

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Check minimum number of events None

9975

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Include endpoints None

9975

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E4_HYTHY_AI_EXCL

Extra metadata

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 9975 7053 2922
Unadjusted prevalence (%) 2.80 3.55 1.86
Mean age at first event (years) 52.41 51.86 53.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.70 [2.05, 3.54] 8.5e-13 617
15 years 0.01 1.53 [1.19, 1.95] 7.7e-4 270
5 years 0.00 2.59 [1.99, 3.39] 2.6e-12 184
1 year 0.00 6.73 [4.99, 9.09] 1.2e-35 91

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYTHY_AI_EXCL – Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
GWS hits:

Survival analyses between endpoints

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Plot

before Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
after Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

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