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Polycystic ovarian syndrome, concortium definition

PheWeb

E4_PCOS_CONCORTIUM

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 L68.0#, N92.5, N92.6
Hospital discharge: ICD-9 626|7041
Hospital discharge: ICD-8 626|70405
Hospital discharge: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74
Hospital discharge: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940
Hospital discharge: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260
Cause of death: ICD-10 L68.0#, N92.5, N92.6
Cause of death: ICD-9 626|7041
Cause of death: ICD-8 626|70405
Cause of death: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74
Cause of death: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940
Cause of death: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints

28991

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E4_PCOS_CONCORTIUM

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6v3

Summary Statistics

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Key figures

All Female Male
Number of individuals 28991 28991 -
Unadjusted prevalence (%) 8.15 14.61 -
Mean age at first event (years) 38.39 38.39 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.57 [0.49, 0.66] 3.5e-14 1659
15 years 0.00 0.41 [0.36, 0.48] 2.8e-34 594
5 years 0.00 0.30 [0.24, 0.38] 4.8e-24 90
1 year 0.00 0.37 [0.23, 0.60] 3.8e-5 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_PCOS_CONCORTIUM – Polycystic ovarian syndrome, concortium definition
GWS hits: 2

Survival analyses between endpoints

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Plot

before Polycystic ovarian syndrome, concortium definition
after Polycystic ovarian syndrome, concortium definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Polycystic ovarian syndrome, concortium definition

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