Enterohaemorrhagic Escherichia coli infection

EHEC

dysentery: Acute inflammation of the intestine associated with infectious diarrhea of various etiologies, generally acquired by eating contaminated food containing toxins, biological derived from bacteria or other microorganisms. Dysentery is characterized initially by watery feces then by bloody mucoid stools. It is often associated with abdominal pain; fever; and dehydration.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 A04.3
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 A04.3
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

34

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

34

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Check minimum number of events None

34

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Include endpoints None

34

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EHEC

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 A04
Name in latin Infectio ab Escherichia coli enterohaemorrhagica

Summary Statistics

Key figures

All Female Male
Number of individuals 34 19 15
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 45.81 43.12 49.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: EHEC – Enterohaemorrhagic Escherichia coli infection
GWS hits:

Survival analyses between endpoints

Plot

before Enterohaemorrhagic Escherichia coli infection
after Enterohaemorrhagic Escherichia coli infection

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Drugs most likely to be purchased after Enterohaemorrhagic Escherichia coli infection