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Anorexia (incl.atypical)

DOID EFO MESH SNOMED PheWeb

F5_ANOREX

anorexia nervosa: A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F50.0, F50.1
Hospital discharge: ICD-9 7830A|3071A
Hospital discharge: ICD-8 784
Cause of death: ICD-10 F50.0, F50.1
Cause of death: ICD-9 7830A|3071A
Cause of death: ICD-8 784

4483

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1749

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Check minimum number of events None

1749

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Include endpoints None

1749

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F5_ANOREX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1749 1375 374
Unadjusted prevalence (%) 0.49 0.69 0.24
Mean age at first event (years) 23.23 21.90 28.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.05 [0.94, 4.46] 7.1e-2 107
15 years 0.01 1.09 [0.59, 2.00] 7.9e-1 35
5 years 0.00 2.68 [1.57, 4.55] 2.7e-4 25
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_ANOREX – Anorexia (incl.atypical)
GWS hits:

Survival analyses between endpoints

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Plot

before Anorexia (incl.atypical)
after Anorexia (incl.atypical)

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Drugs most likely to be purchased after Anorexia (incl.atypical)

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