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Generalized anxiety disorder

DOID EFO MESH SNOMED PheWeb

F5_GAD

generalized anxiety disorder: An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F41.1
Hospital discharge: ICD-9 3000C
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F41.1
Cause of death: ICD-9 3000C
Cause of death: ICD-8 $!$

4062

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4062

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Check minimum number of events None

4062

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Include endpoints None

4062

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F5_GAD

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Perturbatio anxifera generalisata

Summary Statistics

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Key figures

All Female Male
Number of individuals 4062 2908 1154
Unadjusted prevalence (%) 1.14 1.47 0.73
Mean age at first event (years) 40.23 39.87 41.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.94 [1.68, 5.15] 1.7e-4 136
15 years 0.01 2.06 [1.25, 3.39] 4.4e-3 57
5 years 0.01 3.92 [2.52, 6.09] 1.3e-9 32
1 year 0.00 11.86 [6.91, 20.38] 3.2e-19 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_GAD – Generalized anxiety disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Generalized anxiety disorder
after Generalized anxiety disorder

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Drugs most likely to be purchased after Generalized anxiety disorder

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