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Panic disorder

DOID EFO MESH SNOMED PheWeb

F5_PANIC

panic disorder: An anxiety disorder characterized by multiple unexpected panic attacks with persistent concern of recurring attacks. Panic disorder may or may not be accompanied by agoraphobia.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F41.0
Hospital discharge: ICD-9 3000B|3002B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F41.0
Cause of death: ICD-9 3000B|3002B
Cause of death: ICD-8 $!$

4385

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4385

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Check minimum number of events None

4385

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Include endpoints None

4385

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F5_PANIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Angor paroxysmalis episodicus

Summary Statistics

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Key figures

All Female Male
Number of individuals 4385 3126 1259
Unadjusted prevalence (%) 1.23 1.58 0.80
Mean age at first event (years) 37.53 36.44 40.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.28 [1.38, 3.79] 1.4e-3 143
15 years 0.01 1.52 [0.85, 2.71] 1.6e-1 61
5 years 0.01 4.08 [2.46, 6.79] 5.8e-8 44
1 year 0.00 5.33 [2.65, 10.71] 2.6e-6 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_PANIC – Panic disorder
GWS hits:

Survival analyses between endpoints

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Plot

before Panic disorder
after Panic disorder

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