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Falls/tendenct to fall

DOID EFO MESH PheWeb

FALLS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 R29.6, W00-W19
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 R29.6, W00-W19
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

2047

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2047

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Check minimum number of events None

2047

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Include endpoints None

2047

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FALLS

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 2047 738 1309
Unadjusted prevalence (%) 0.58 0.37 0.83
Mean age at first event (years) 72.88 70.97 73.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.50 38.98 [25.28, 60.08] 8.5e-62 1410
15 years 0.01 1.10 [0.56, 2.14] 7.8e-1 25
5 years 0.00 3.42 [1.37, 8.57] 8.6e-3 46
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FALLS – Falls/tendenct to fall
GWS hits:

Survival analyses between endpoints

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Plot

before Falls/tendenct to fall
after Falls/tendenct to fall

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Falls/tendenct to fall

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