Other disorders of eye and adnexa

H7_EYEOTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H55-H59
Cause of death: ICD-10 H55-H59

3450

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

3450

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Check minimum number of events None

3450

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H7_EYEOTH

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Other disorders of eye and adnexa based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 3638 2475 1163
Unadjusted prevalence (%) 1.02 1.25 0.74
Mean age at first event (years) 48.55 47.93 49.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.74 [1.08, 2.80] 2.2e-2 233
15 years 0.01 0.99 [0.67, 1.47] 9.8e-1 98
5 years 0.00 2.02 [1.36, 3.00] 4.8e-4 69
1 year 0.00 2.66 [1.50, 4.71] 8.0e-4 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_EYEOTH – Other disorders of eye and adnexa
GWS hits:

Survival analyses between endpoints

Plot

before Other disorders of eye and adnexa
after Other disorders of eye and adnexa

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Drugs most likely to be purchased after Other disorders of eye and adnexa