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Disorders of eyelid, lacrimal system and orbit

DOID EFO MESH SNOMED PheWeb

H7_LIDLACRIMALORBIT

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H00-H06
Cause of death: ICD-10 H00-H06

28366

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

28366

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Check minimum number of events None

28366

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Include endpoints

29193

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H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 29193 18860 10333
Unadjusted prevalence (%) 8.21 9.51 6.57
Mean age at first event (years) 57.08 55.21 60.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.86 [1.60, 2.15] 9.9e-17 2507
15 years 0.01 1.14 [0.98, 1.31] 8.1e-2 1194
5 years 0.00 2.08 [1.83, 2.37] 4.6e-29 776
1 year 0.00 3.07 [2.58, 3.66] 7.0e-36 219

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_LIDLACRIMALORBIT – Disorders of eyelid, lacrimal system and orbit
GWS hits:

Survival analyses between endpoints

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Plot

before Disorders of eyelid, lacrimal system and orbit
after Disorders of eyelid, lacrimal system and orbit

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Drugs most likely to be purchased after Disorders of eyelid, lacrimal system and orbit

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