Myopia

H7_MYOPIA

obsolete_myopia: ['A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.']

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H52.1
Hospital discharge: ICD-9 3671
Hospital discharge: ICD-8 37002
Cause of death: ICD-10 H52.1
Cause of death: ICD-9 3671
Cause of death: ICD-8 37002

3129

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3129

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Check minimum number of events None

3129

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Include endpoints None

3129

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H7_MYOPIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H52
Name in latin Myopia

Summary Statistics

Key figures

All Female Male
Number of individuals 3129 2107 1022
Unadjusted prevalence (%) 0.88 1.06 0.65
Mean age at first event (years) 38.41 37.91 39.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.68 [0.91, 3.11] 9.8e-2 99
15 years 0.01 0.95 [0.47, 1.92] 8.8e-1 48
5 years 0.00 1.38 [0.60, 3.16] 4.5e-1 25
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_MYOPIA – Myopia
GWS hits: 2

Survival analyses between endpoints

Plot

before Myopia
after Myopia

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