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Pterygium

DOID EFO MESH SNOMED PheWeb

H7_PTERYGIUM

pterygium: A wedge-shaped fibrovascular lesion arising from the bulbar conjunctiva and extending to the cornea. It is caused by chronic exposure to solar ultraviolet radiation, heat, and dust. It may cause severe vision loss. Studies have linked pterygium to neoplastic proliferation and suggest that it may be a stem cell disorder.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H11.0
Hospital discharge: ICD-9 3724
Hospital discharge: ICD-8 372
Cause of death: ICD-10 H11.0
Cause of death: ICD-9 3724
Cause of death: ICD-8 372

852

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

688

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Check minimum number of events None

688

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Include endpoints None

688

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H7_PTERYGIUM

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H11
Name in latin Pterygium

Summary Statistics

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Key figures

All Female Male
Number of individuals 688 241 447
Unadjusted prevalence (%) 0.19 0.12 0.28
Mean age at first event (years) 58.76 55.60 60.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.31 [0.91, 1.89] 1.4e-1 89
15 years 0.01 0.91 [0.63, 1.31] 6.1e-1 45
5 years 0.00 0.74 [0.38, 1.44] 3.7e-1 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_PTERYGIUM – Pterygium
GWS hits:

Survival analyses between endpoints

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Plot

before Pterygium
after Pterygium

loading spinner Loading survival analyses plot