Retinal detachment with retinal break

H7_RETINALDETACHBREAK

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H33.0
Hospital discharge: ICD-9 3610
Hospital discharge: ICD-8 37602
Cause of death: ICD-10 H33.0
Cause of death: ICD-9 3610
Cause of death: ICD-8 37602

3411

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3385

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Check minimum number of events None

3385

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Include endpoints None

3385

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H7_RETINALDETACHBREAK

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H33
Name in latin Amotio/ablatio retinae cum ruptura

Summary Statistics

Key figures

All Female Male
Number of individuals 3385 1440 1945
Unadjusted prevalence (%) 0.95 0.73 1.24
Mean age at first event (years) 58.78 57.06 60.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.38 [0.99, 1.92] 5.4e-2 389
15 years 0.01 1.08 [0.80, 1.45] 6.3e-1 207
5 years 0.00 1.68 [1.26, 2.24] 4.6e-4 98
1 year 0.00 1.95 [1.21, 3.14] 6.2e-3 21

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_RETINALDETACHBREAK – Retinal detachment with retinal break
GWS hits: 3

Survival analyses between endpoints

Plot

before Retinal detachment with retinal break
after Retinal detachment with retinal break

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Drugs most likely to be purchased after Retinal detachment with retinal break