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Retinoschisis and retinal cysts

DOID EFO MESH SNOMED PheWeb

H7_RETINOCHISISCYST

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H33.1
Hospital discharge: ICD-9 3611
Hospital discharge: ICD-8 37603
Cause of death: ICD-10 H33.1
Cause of death: ICD-9 3611
Cause of death: ICD-8 37603

534

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

534

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Check minimum number of events None

534

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Include endpoints None

534

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H7_RETINOCHISISCYST

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H33
Name in latin Retinoschisis et cystae retinales

Summary Statistics

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Key figures

All Female Male
Number of individuals 534 247 287
Unadjusted prevalence (%) 0.15 0.12 0.18
Mean age at first event (years) 60.28 59.16 61.25

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.57 [0.26, 1.24] 1.6e-1 37
15 years 0.00 0.48 [0.22, 1.05] 6.7e-2 21
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINOCHISISCYST – Retinoschisis and retinal cysts
GWS hits: 1

Survival analyses between endpoints

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Plot

before Retinoschisis and retinal cysts
after Retinoschisis and retinal cysts

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Retinoschisis and retinal cysts

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