Retinopathy of prematurity

H7_RETINOPATPREMAT

retinopathy of prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H35.1
Hospital discharge: ICD-9 3622A
Hospital discharge: ICD-8 37704
Cause of death: ICD-10 H35.1
Cause of death: ICD-9 3622A
Cause of death: ICD-8 37704

82

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

82

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Check minimum number of events None

82

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Include endpoints None

82

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H7_RETINOPATPREMAT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H35
Name in latin Retinopathia praematuritatis

Summary Statistics

Key figures

All Female Male
Number of individuals 82 50 32
Unadjusted prevalence (%) 0.02 0.03 0.02
Mean age at first event (years) 35.79 38.47 31.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_RETINOPATPREMAT – Retinopathy of prematurity
GWS hits: 1

Survival analyses between endpoints

Plot

before Retinopathy of prematurity
after Retinopathy of prematurity

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Drugs most likely to be purchased after Retinopathy of prematurity