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Sudden idiopathic hearing loss

DOID EFO MESH SNOMED PheWeb

H8_HL_IDIOP

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H91.2
Hospital discharge: ICD-9 3882
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H91.2
Cause of death: ICD-9 3882
Cause of death: ICD-8 $!$

2634

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2634

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Check minimum number of events None

2634

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Include endpoints None

2634

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H8_HL_IDIOP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H91
Name in latin Hypacusis acuta idiopathica

Summary Statistics

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Key figures

All Female Male
Number of individuals 2634 1370 1264
Unadjusted prevalence (%) 0.74 0.69 0.80
Mean age at first event (years) 57.12 55.14 59.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.26 [0.80, 1.97] 3.1e-1 215
15 years 0.01 0.86 [0.58, 1.27] 4.4e-1 98
5 years 0.00 1.78 [1.23, 2.58] 2.4e-3 60
1 year 0.00 1.95 [1.04, 3.63] 3.6e-2 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_HL_IDIOP – Sudden idiopathic hearing loss
GWS hits: 1

Survival analyses between endpoints

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Plot

before Sudden idiopathic hearing loss
after Sudden idiopathic hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Sudden idiopathic hearing loss

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