≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Other specified/unspecified hearing loss

DOID EFO MESH SNOMED PheWeb

H8_HL_NAS

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H91.8, H91.9
Hospital discharge: ICD-9 389[8-9]
Hospital discharge: ICD-8 389
Cause of death: ICD-10 H91.8, H91.9
Cause of death: ICD-9 389[8-9]
Cause of death: ICD-8 389

2190

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1956

diagram downward connector

Check minimum number of events None

1956

diagram downward connector

Include endpoints None

1956

diagram downward connector
H8_HL_NAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1956 948 1008
Unadjusted prevalence (%) 0.55 0.48 0.64
Mean age at first event (years) 59.60 55.29 63.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.03 [1.92, 4.79] 2.0e-6 305
15 years 0.01 1.55 [1.11, 2.18] 1.1e-2 112
5 years 0.01 4.03 [3.07, 5.29] 1.2e-23 128
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: H8_HL_NAS – Other specified/unspecified hearing loss
GWS hits:

Survival analyses between endpoints

↥

Plot

before Other specified/unspecified hearing loss
after Other specified/unspecified hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other specified/unspecified hearing loss

↥