Chronic viral hepatitis

HEPATITIS_CHRONIC_VIRAL

hepatitis A virus infection: Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 B18
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 B18
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1565

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1565

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Check minimum number of events None

1565

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Include endpoints None

1565

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HEPATITIS_CHRONIC_VIRAL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 B15-B19
Name in latin Hepatitis viralis chronica

Summary Statistics

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Key figures

All Female Male
Number of individuals 1565 655 910
Unadjusted prevalence (%) 0.44 0.33 0.58
Mean age at first event (years) 38.27 37.00 39.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.28 20.55 [11.05, 38.22] 1.3e-21 101
15 years 0.06 8.92 [4.80, 16.59] 4.7e-12 37
5 years 0.02 18.84 [10.77, 32.99] 8.8e-25 35
1 year 0.01 50.23 [27.38, 92.13] 1.1e-36 22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: HEPATITIS_CHRONIC_VIRAL – Chronic viral hepatitis
GWS hits:

Survival analyses between endpoints

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Plot

before Chronic viral hepatitis
after Chronic viral hepatitis

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Drugs most likely to be purchased after Chronic viral hepatitis

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