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Hypothyroidism, drug reimbursement

DOID EFO MESH SNOMED PheWeb

HYPOTHY_REIMB

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

KELA reimbursements: KELA codes 104

11305

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Check pre-conditions, main-only, mode, ICD version None

11305

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Check minimum number of events None

11305

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Include endpoints None

11305

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HYPOTHY_REIMB

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 11305 9343 1962
Unadjusted prevalence (%) 3.18 4.71 1.25
Mean age at first event (years) 46.90 46.02 51.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.00 [0.82, 1.23] 9.8e-1 1094
15 years 0.01 0.77 [0.64, 0.92] 4.5e-3 473
5 years 0.00 0.87 [0.70, 1.08] 2.2e-1 130
1 year 0.00 1.17 [0.79, 1.72] 4.3e-1 30

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: HYPOTHY_REIMB – Hypothyroidism, drug reimbursement
GWS hits: 21

Survival analyses between endpoints

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Plot

before Hypothyroidism, drug reimbursement
after Hypothyroidism, drug reimbursement

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, drug reimbursement

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