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Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders

DOID EFO MESH PheWeb

KRA_PSY_ANYMENTAL_SUICID_PREG_NERV

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 O99.3
Hospital discharge: ICD-9 6484X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O99.3
Cause of death: ICD-9 6484X
Cause of death: ICD-8 $!$

1854

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1854

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Check minimum number of events None

1854

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Include endpoints

3236

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KRA_PSY_ANYMENTAL_SUICID_PREG_NERV

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 O99
Name in latin Perturbationes psychicae et morbi systematis nervosi complicantes graviditatem, partum et puerperium

Similar endpoints

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List of similar endpoints to Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 3236 2535 701
Unadjusted prevalence (%) 0.91 1.28 0.45
Mean age at first event (years) 33.61 30.88 43.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 9.68 [5.98, 15.67] 2.5e-20 498
15 years 0.01 2.23 [1.47, 3.38] 1.5e-4 64
5 years 0.00 2.22 [1.29, 3.81] 3.9e-3 17
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_ANYMENTAL_SUICID_PREG_NERV – Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders
GWS hits:

Survival analyses between endpoints

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Plot

before Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders
after Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders

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Drugs most likely to be purchased after Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders

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