Alergic contact dermatitis

L12_ALLERGICCONTACT

allergic contact dermatitis: An inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. It consists of a delayed type of allergic reaction at the affected site with resulting red, swollen, and blistered skin that may itch or leak.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L23
Hospital discharge: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L23
Cause of death: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
Cause of death: ICD-8 $!$

3965

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3965

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Check minimum number of events None

3965

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Include endpoints None

3965

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L12_ALLERGICCONTACT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Eczema (allergicum) ex contactu

Summary Statistics

Key figures

All Female Male
Number of individuals 3965 3110 855
Unadjusted prevalence (%) 1.11 1.57 0.54
Mean age at first event (years) 47.02 45.98 50.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.39 [0.83, 2.33] 2.1e-1 168
15 years 0.01 1.08 [0.66, 1.76] 7.7e-1 90
5 years 0.00 1.73 [1.09, 2.75] 1.9e-2 38
1 year 0.00 2.56 [1.28, 5.10] 7.7e-3 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_ALLERGICCONTACT – Alergic contact dermatitis
GWS hits: 1

Survival analyses between endpoints

Plot

before Alergic contact dermatitis
after Alergic contact dermatitis

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Drugs most likely to be purchased after Alergic contact dermatitis