≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Dermatitis herpetiformis

DOID EFO MESH SNOMED PheWeb

L12_DERMATHERP

dermatitis herpetiformis: Dermatitis herpetiformis (DH) is a chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. DH may also appear as a consequence of gluten intolerance.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 L13.0
Hospital discharge: ICD-9 6940A|6942
Hospital discharge: ICD-8 693
Cause of death: ICD-10 L13.0
Cause of death: ICD-9 6940A|6942
Cause of death: ICD-8 693

673

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

446

diagram downward connector

Check minimum number of events None

446

diagram downward connector

Include endpoints None

446

diagram downward connector
L12_DERMATHERP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L13
Name in latin Dermatitis herpetiformis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 446 249 197
Unadjusted prevalence (%) 0.13 0.13 0.13
Mean age at first event (years) 44.99 42.48 48.16

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.46 [0.17, 1.28] 1.4e-1 40
15 years 0.00 0.48 [0.19, 1.21] 1.2e-1 20
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: L12_DERMATHERP – Dermatitis herpetiformis
GWS hits:

Survival analyses between endpoints

↥

Plot

before Dermatitis herpetiformis
after Dermatitis herpetiformis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Dermatitis herpetiformis

↥