Exfoliative dermatitis

L12_EXFOLIATIVE

atopic eczema: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L26
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L26
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 L26

197150

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

275

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Check minimum number of events None

275

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Include endpoints None

275

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L12_EXFOLIATIVE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Erythrodermia universalis NAS

Summary Statistics

Key figures

All Female Male
Number of individuals 275 78 197
Unadjusted prevalence (%) 0.08 0.04 0.13
Mean age at first event (years) 58.12 52.22 60.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_EXFOLIATIVE – Exfoliative dermatitis
GWS hits:

Survival analyses between endpoints

Plot

before Exfoliative dermatitis
after Exfoliative dermatitis

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Drugs most likely to be purchased after Exfoliative dermatitis