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Hidradenitis suppurativa

DOID EFO MESH SNOMED PheWeb

L12_HIDRADENITISSUP

hidradenitis suppurativa: a common (though rarely diagnosed), chronic skin disease characterized by clusters of abscesses or subcutaneous boil-like "infections" (oftentimes free of actual bacteria) that most commonly affects apocrine sweat gland bearing areas, such as the underarms, under the breasts, inner thighs, groin and buttocks.The disease is not contagious. There are indications that it is hereditary among certain ethnic groups and autoimmune in nature. Onset is most common in the late teens and early 20's.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L73.2
Hospital discharge: ICD-9 7058C
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L73.2
Cause of death: ICD-9 7058C
Cause of death: ICD-8 $!$

834

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

834

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Check minimum number of events None

834

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Include endpoints None

834

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L12_HIDRADENITISSUP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L73
Name in latin Hidradenitis suppurativa

Summary Statistics

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Key figures

All Female Male
Number of individuals 834 568 266
Unadjusted prevalence (%) 0.23 0.29 0.17
Mean age at first event (years) 41.62 39.55 46.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.33 [1.00, 5.44] 5.1e-2 39
15 years 0.01 1.81 [0.83, 3.95] 1.4e-1 20
5 years 0.00 2.58 [1.04, 6.42] 4.2e-2 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_HIDRADENITISSUP – Hidradenitis suppurativa
GWS hits: 4

Survival analyses between endpoints

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Plot

before Hidradenitis suppurativa
after Hidradenitis suppurativa

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hidradenitis suppurativa

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