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Localized scleroderma [morphea]

DOID EFO MESH SNOMED PheWeb

L12_LOCALSCLERODERMA

localised scleroderma: Localized scleroderma is the skin localized form of scleroderma (see this term) characterized by fibrosis of the skin causing cutaneous plaques or strips.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L94.0
Hospital discharge: ICD-9 7010A
Hospital discharge: ICD-8 70100
Cause of death: ICD-10 L94.0
Cause of death: ICD-9 7010A
Cause of death: ICD-8 70100

320

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

320

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Check minimum number of events None

320

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Include endpoints None

320

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L12_LOCALSCLERODERMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L94
Name in latin Scleroderma circumscriptum

Summary Statistics

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Key figures

All Female Male
Number of individuals 320 263 57
Unadjusted prevalence (%) 0.09 0.13 0.04
Mean age at first event (years) 49.81 50.23 47.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.19 [0.38, 3.71] 7.7e-1 16
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_LOCALSCLERODERMA – Localized scleroderma [morphea]
GWS hits:

Survival analyses between endpoints

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Plot

before Localized scleroderma [morphea]
after Localized scleroderma [morphea]

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Localized scleroderma [morphea]

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