Cicatricial pemphigoid

L12_PEMPHIGOID_CICA

mucous membrane pemphigoid: Mucous membrane pemphigoid is a bullous dermatosis characterised clinically by blistering of the mucous membranes followed by scarring, and immunologically by IgG, IgA and/or C3 deposits on the epidermal basement membrane.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L12.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L12.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

52

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

52

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Check minimum number of events None

52

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Include endpoints None

52

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L12_PEMPHIGOID_CICA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L12
Name in latin Pemphigoides cicatricalis

Summary Statistics

Key figures

All Female Male
Number of individuals 52 39 13
Unadjusted prevalence (%) 0.01 0.02 0.01
Mean age at first event (years) 59.83 59.05 62.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_PEMPHIGOID_CICA – Cicatricial pemphigoid
GWS hits:

Survival analyses between endpoints

Plot

before Cicatricial pemphigoid
after Cicatricial pemphigoid

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Drugs most likely to be purchased after Cicatricial pemphigoid