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Severe bullous disorders, KELA reimbursement

DOID EFO MESH PheWeb

L12_PEMPHIKELA

vesiculobullous skin disease: Skin diseases characterized by local or general distributions of vesicles and bullae (i.e. blisters). Both vesicles and bullae are fluid-filled lesions, distinguished by size (vesicles being less than 5–10 mm and bullae being larger than 5–10 mm). Vesiculobullous diseases are classified according to the site and mode of blister formation. Lesions can appear spontaneously or be precipitated by infection, trauma, or sunlight. Etiologies include immunologic and genetic factors. In the case of vesiculobullous diseases which are also immune disorders, the term immunobullous is sometimes used. (From Scientific American Medicine, 1990, and Wikipedia)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

KELA reimbursements: KELA codes 135

44

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Check pre-conditions, main-only, mode, ICD version None

44

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Check minimum number of events None

44

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Include endpoints None

44

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L12_PEMPHIKELA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 44 24 20
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 57.87 55.75 60.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PEMPHIKELA – Severe bullous disorders, KELA reimbursement
GWS hits:

Survival analyses between endpoints

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Plot

before Severe bullous disorders, KELA reimbursement
after Severe bullous disorders, KELA reimbursement

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Severe bullous disorders, KELA reimbursement

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