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Other and unspecified disorders of skin and subcutaneous tissue

DOID EFO MESH SNOMED PheWeb

L12_SKINSUBCUTISNAS

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L98.80, L98.88, L98.9
Hospital discharge: ICD-9 7019X|7098|7099
Hospital discharge: ICD-8 70198|7090[8-9]
Hospital discharge: excluded ICD-9 7098A|7098B
Cause of death: ICD-10 L98.80, L98.88, L98.9
Cause of death: ICD-9 7019X|7098|7099
Cause of death: ICD-8 70198|7090[8-9]
Cause of death: excluded ICD-9 7098A|7098B

1811

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1806

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Check minimum number of events None

1806

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Include endpoints None

1806

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L12_SKINSUBCUTISNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1806 1114 692
Unadjusted prevalence (%) 0.51 0.56 0.44
Mean age at first event (years) 52.38 49.96 56.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.06 [1.31, 3.26] 1.9e-3 188
15 years 0.01 1.33 [0.92, 1.91] 1.2e-1 80
5 years 0.00 2.67 [1.83, 3.89] 3.3e-7 53
1 year 0.00 6.13 [3.78, 9.93] 2.0e-13 22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_SKINSUBCUTISNAS – Other and unspecified disorders of skin and subcutaneous tissue
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other and unspecified disorders of skin and subcutaneous tissue
after Other and unspecified disorders of skin and subcutaneous tissue

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Drugs most likely to be purchased after Other and unspecified disorders of skin and subcutaneous tissue

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