Disorders of breast

N14_BREAST

breast disease: A disease involving the breast.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

198506

diagram downward connector

Check conditions None

198506

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 N60-N64
Cause of death: ICD-10 N60-N64

12770

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

12770

diagram downward connector

Check minimum number of events None

12770

diagram downward connector
N14_BREAST

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 15404 15404 -
Unadjusted prevalence (%) 4.33 7.76 -
Mean age at first event (years) 46.22 46.22 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.67 [0.55, 0.81] 5.1e-5 678
15 years 0.00 0.52 [0.43, 0.63] 4.7e-11 294
5 years 0.00 0.80 [0.63, 1.01] 6.1e-2 106
1 year 0.00 0.69 [0.41, 1.15] 1.6e-1 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_BREAST – Disorders of breast
GWS hits: 7

Survival analyses between endpoints

Plot

before Disorders of breast
after Disorders of breast

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of breast