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Disorders resulting from impaired renal tubular function

DOID EFO MESH SNOMED PheWeb

N14_DISIMPAIRRENTUB

urinary system disease: A disease involving the renal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 N25
Hospital discharge: ICD-9 588
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 N25
Cause of death: ICD-9 588
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

800

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N14_DISIMPAIRRENTUB

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N25-N29
Name in latin Morbositates ex dysfunctione tubulari renali

Summary Statistics

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Key figures

All Female Male
Number of individuals 800 359 441
Unadjusted prevalence (%) 0.22 0.18 0.28
Mean age at first event (years) 55.94 53.92 57.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.08 [2.04, 12.66] 4.8e-4 125
15 years 0.01 1.74 [0.83, 3.66] 1.4e-1 32
5 years 0.01 7.50 [4.46, 12.63] 3.3e-14 62
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_DISIMPAIRRENTUB – Disorders resulting from impaired renal tubular function
GWS hits: 2

Survival analyses between endpoints

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Plot

before Disorders resulting from impaired renal tubular function
after Disorders resulting from impaired renal tubular function

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders resulting from impaired renal tubular function

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