Dysplasia of cervi uteri

N14_DYSPLACERVUT

dysplasia of cervix: Abnormal development of immature squamous epithelial cells of the uterine cervix, a term used to describe premalignant cytological changes in the cervical epithelium. These atypical cells do not penetrate the epithelial basement membrane.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 N87
Hospital discharge: ICD-9 6221
Hospital discharge: ICD-8 621
Hospital discharge: excluded ICD-8 62191
Cause of death: ICD-10 N87
Cause of death: ICD-9 6221
Cause of death: ICD-8 621
Cause of death: excluded ICD-8 62191

9505

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7753

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Check minimum number of events None

7753

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Include endpoints None

7753

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N14_DYSPLACERVUT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N80-N98
Name in latin Dysplasia cervicis uteri

Summary Statistics

Key figures

All Female Male
Number of individuals 7753 7753 -
Unadjusted prevalence (%) 2.18 3.91 -
Mean age at first event (years) 36.57 36.57 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.51 [1.10, 2.06] 9.9e-3 203
15 years 0.01 1.05 [0.77, 1.43] 7.7e-1 81
5 years 0.00 1.19 [0.75, 1.89] 4.7e-1 23
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_DYSPLACERVUT – Dysplasia of cervi uteri
GWS hits:

Survival analyses between endpoints

Plot

before Dysplasia of cervi uteri
after Dysplasia of cervi uteri

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Drugs most likely to be purchased after Dysplasia of cervi uteri