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Other specified disorders of kidney and ureter

DOID EFO MESH PheWeb

N14_OTHETNASKIDUR

renal artery obstruction: Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular).

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 N28.0, N28.8, N28.9
Hospital discharge: ICD-9 593[0-1]|5938
Hospital discharge: ICD-8 59322
Hospital discharge: excluded ICD-8 5938B
Cause of death: ICD-10 N28.0, N28.8, N28.9
Cause of death: ICD-9 593[0-1]|5938
Cause of death: ICD-8 59322
Cause of death: excluded ICD-8 5938B

880

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

806

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Check minimum number of events None

806

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Include endpoints None

806

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N14_OTHETNASKIDUR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 806 433 373
Unadjusted prevalence (%) 0.23 0.22 0.24
Mean age at first event (years) 50.28 46.36 54.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.39 [2.64, 7.29] 1.2e-8 116
15 years 0.01 1.88 [1.10, 3.20] 2.0e-2 42
5 years 0.01 4.04 [2.48, 6.59] 2.0e-8 39
1 year 0.00 10.66 [6.07, 18.71] 1.6e-16 25

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_OTHETNASKIDUR – Other specified disorders of kidney and ureter
GWS hits:

Survival analyses between endpoints

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Plot

before Other specified disorders of kidney and ureter
after Other specified disorders of kidney and ureter

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Drugs most likely to be purchased after Other specified disorders of kidney and ureter

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