Renal failure

N14_RENFAIL

kidney failure: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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N14_RENFAIL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 12609 4244 8365
Unadjusted prevalence (%) 3.54 2.14 5.32
Mean age at first event (years) 67.03 65.01 68.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 8.51 [6.95, 10.42] 3.5e-95 4245
15 years 0.01 1.91 [1.54, 2.38] 5.5e-9 767
5 years 0.01 6.41 [5.48, 7.50] <1e-100 1409
1 year 0.01 34.23 [30.08, 38.95] <1e-100 2006

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_RENFAIL – Renal failure
GWS hits: 3

Survival analyses between endpoints

Plot

before Renal failure
after Renal failure

loading spinner Loading survival analyses plot