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Tubulo-interstitial nephritis, not spesified as acute or chronic

DOID EFO MESH SNOMED PheWeb

N14_TUBULOINTNEPHRNAS

pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 N12
Hospital discharge: ICD-9 5909
Hospital discharge: ICD-8 5909
Cause of death: ICD-10 N12
Cause of death: ICD-9 5909
Cause of death: ICD-8 5909

1968

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1968

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Check minimum number of events None

1968

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Include endpoints None

1968

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N14_TUBULOINTNEPHRNAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N10-N16
Name in latin Nephritis tubulo-interstitialis sine specificatione utrum acuta an chronica

Summary Statistics

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Key figures

All Female Male
Number of individuals 1968 1192 776
Unadjusted prevalence (%) 0.55 0.60 0.49
Mean age at first event (years) 53.31 45.65 65.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.96 [2.51, 6.24] 3.5e-9 485
15 years 0.01 1.26 [0.86, 1.84] 2.3e-1 114
5 years 0.01 4.97 [3.79, 6.52] 3.1e-31 168
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_TUBULOINTNEPHRNAS – Tubulo-interstitial nephritis, not spesified as acute or chronic
GWS hits:

Survival analyses between endpoints

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Plot

before Tubulo-interstitial nephritis, not spesified as acute or chronic
after Tubulo-interstitial nephritis, not spesified as acute or chronic

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Drugs most likely to be purchased after Tubulo-interstitial nephritis, not spesified as acute or chronic

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