Spontaneous abortion

O15_ABORT_SPONTAN

habitual abortion: Three or more consecutive spontaneous abortions.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 O03
Hospital discharge: ICD-9 634
Hospital discharge: ICD-8 643
Cause of death: ICD-10 O03
Cause of death: ICD-9 634
Cause of death: ICD-8 643

21852

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

15651

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Check minimum number of events None

15651

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Include endpoints None

15651

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O15_ABORT_SPONTAN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O00-O08
Name in latin Abortus spontaneus

Summary Statistics

Key figures

All Female Male
Number of individuals 15651 15651 -
Unadjusted prevalence (%) 4.40 7.89 -
Mean age at first event (years) 30.45 30.45 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.49 [0.38, 0.64] 1.1e-7 303
15 years 0.00 0.34 [0.25, 0.46] 3.3e-12 91
5 years 0.00 0.21 [0.11, 0.40] 1.5e-6 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_ABORT_SPONTAN – Spontaneous abortion
GWS hits:

Survival analyses between endpoints

Plot

before Spontaneous abortion
after Spontaneous abortion

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Drugs most likely to be purchased after Spontaneous abortion