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Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

PheWeb

O15_ICP_WIDE

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 O26.6
Hospital discharge: ICD-9 6467
Hospital discharge: ICD-8 6390
Cause of death: ICD-10 O26.6
Cause of death: ICD-9 6467
Cause of death: ICD-8 6390

2274

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2274

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Check minimum number of events None

2274

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Include endpoints None

2274

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O15_ICP_WIDE

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O26
Name in latin Morbositates hepatis in graviditate, intra labores et/sive in puerperio

Summary Statistics

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Key figures

All Female Male
Number of individuals 2274 2274 -
Unadjusted prevalence (%) 0.64 1.15 -
Mean age at first event (years) 29.96 29.96 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.66 [0.35, 1.24] 2.0e-1 32
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_ICP_WIDE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
GWS hits: 22

Survival analyses between endpoints

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Plot

before Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
after Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

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Drugs most likely to be purchased after Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

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