Diabetes mellitus in pregnancy

O15_PREG_DM

gestational diabetes: Carbohydrate intolerance first diagnosed during pregnancy.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 O24
Hospital discharge: ICD-9 6480
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O24
Cause of death: ICD-9 6480
Cause of death: ICD-8 $!$

12474

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

12469

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Check minimum number of events None

12469

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Include endpoints None

12469

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O15_PREG_DM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O20-O29
Name in latin Diabetes mellitus gravidarum

Summary Statistics

Key figures

All Female Male
Number of individuals 12469 12469 -
Unadjusted prevalence (%) 3.50 6.28 -
Mean age at first event (years) 31.63 31.63 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.28 [1.64, 3.16] 7.8e-7 81
15 years 0.01 1.66 [1.08, 2.55] 2.0e-2 29
5 years 0.00 2.84 [1.47, 5.47] 1.9e-3 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_PREG_DM – Diabetes mellitus in pregnancy
GWS hits:

Survival analyses between endpoints

Plot

before Diabetes mellitus in pregnancy
after Diabetes mellitus in pregnancy

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Drugs most likely to be purchased after Diabetes mellitus in pregnancy