Respiratory distress of newborn

P16_RESPI_DISTR_NEWBO

newborn respiratory distress syndrome: Infant acute respiratory distress syndrome is a lung disorder that affects premature infants caused by developmental insufficiency of surfactant production and structural immaturity of the lungs. The symptoms usually appear shortly after birth and may include tachypnea, tachycardia, chest wall retractions (recession), expiratory grunting, nasal flaring and cyanosis during breathing efforts.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 P22
Cause of death: ICD-10 P22

327

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

327

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Check minimum number of events None

327

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Include endpoints None

327

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P16_RESPI_DISTR_NEWBO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 P2
Name in latin Dyspnoea neonatalis

Summary Statistics

Key figures

All Female Male
Number of individuals 327 156 171
Unadjusted prevalence (%) 0.09 0.08 0.11
Mean age at first event (years) 0.43 0.83 0.06

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: P16_RESPI_DISTR_NEWBO – Respiratory distress of newborn
GWS hits:

Survival analyses between endpoints

Plot

before Respiratory distress of newborn
after Respiratory distress of newborn

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Drugs most likely to be purchased after Respiratory distress of newborn