Exclusion endpoint for clefts

Q17_CLEFT_PALATE_EXCLUDE

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Primary healthcare outpatient ICD-10: Q38.00, Q38.30, Q38.50, Q38.60, Q38.80, Q86, Q87, Q91
Hospital Discharge: ICD-10 Q38.00, Q38.30, Q38.50, Q38.60, Q38.80, Q86, Q87, Q91
Cause of death: ICD-10 Q38.00, Q38.30, Q38.50, Q38.60, Q38.80, Q86, Q87, Q91

515

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

515

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Check minimum number of events None

515

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Include endpoints None

515

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Q17_CLEFT_PALATE_EXCLUDE

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

List of similar endpoints to Exclusion endpoint for clefts based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 515 272 243
Unadjusted prevalence (%) 0.14 0.14 0.15
Mean age at first event (years) 26.28 27.35 25.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.23 15.40 [8.12, 29.21] 5.8e-17 21
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: Q17_CLEFT_PALATE_EXCLUDE – Exclusion endpoint for clefts
GWS hits:

Survival analyses between endpoints

Plot

before Exclusion endpoint for clefts
after Exclusion endpoint for clefts

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Drugs most likely to be purchased after Exclusion endpoint for clefts